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Updated: 14 hours 33 min ago

Amgen's BiTE® antibody blinatumomab (AMG 103) achieved high rate of complete response

Thu, 05/17/2012 - 23:00
Amgen (NASDAQ:AMGN) announced updated results from a Phase 2 study that showed treatment with blinatumomab (AMG 103) helped achieve a high-rate of complete response (CR) in 72 percent of adult patients with relapsed or refractory B-precursor acute lymphoblastic leukemia (ALL) treated in the study.


Merck total revenues increase 3.2% to € 2.6 billion

Thu, 05/17/2012 - 23:00
The Merck Group's first-quarter 2012 total revenues rose 3.2% to € 2,645 million compared to € 2,564 million in the first quarter of 2011. Sales for the Group increased 3.5% to € 2,564 million in first quarter compared to € 2,478 million in the year-ago quarter.


Pfizer provides topline results from Phase 3 study of Torisel®

Wed, 05/16/2012 - 23:00
Pfizer Inc announced that the Phase 3 INTORSECT (B1771003) study, evaluating TORISEL® (temsirolimus) in patients with advanced renal cell carcinoma (RCC) whose disease had progressed on or after SUTENT® (sunitinib malate) therapy, did not meet the primary endpoint of prolonging progression free survival (PFS) when compared to sorafenib.


In drug-approval race, US FDA ahead of Canada, Europe

Wed, 05/16/2012 - 23:00
The U.S. Food and Drug Administration (FDA) generally approves drug therapies faster and earlier than its counterparts in Canada and Europe, according to a new study by Yale School of Medicine researchers. The study counters perceptions that the drug approval process in the United States is especially slow.


GlaxoSmithKline to fully acquire Cellzome for £61 million

Tue, 05/15/2012 - 23:00
GlaxoSmithKline plc (GSK) has entered into an agreement to acquire those shares it does not currently own in Cellzome, a leader in the development and advancement of proteomics technologies, for £61 million (US$99 million) in cash.


Bristol-Myers Squibb Foundation Announces $15 Million Expansion of Together on Diabetes® to China and India

Tue, 05/15/2012 - 23:00
The Bristol-Myers Squibb Foundation today announced the expansion of its Together on Diabetes® initiative to China and India, pledging $15 million over five years to help these developing nations with rapidly growing numbers of type 2 diabetes patients.


Bristol-Myers Squibb and Tsinghua University Enter Strategic Partnership

Tue, 05/15/2012 - 10:00
Bristol-Myers Squibb Company (NYSE:BMY) and Tsinghua University of Beijing, China, today announced the formation of a multi-year strategic partnership. Under the agreement, Bristol-Myers Squibb will fund research efforts at Tsinghua University's School of Life Sciences to identify and validate novel targets in oncology and immunoscience.


Blood pressure drugs don't protect against colorectal cancer

Mon, 05/14/2012 - 23:00
A new study has found that, contrary to current thinking, taking beta blockers that treat high blood pressure does not decrease a person's risk of developing colorectal cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also revealed that even long-term use or subtypes of beta blockers showed no reduction of colorectal cancer risk.


Statistically significant clinical phase III results of Lu AA21004

Mon, 05/14/2012 - 15:00
H. Lundbeck A/S (Lundbeck) today announced positive top-line results from three recently completed phase III clinical studies of Lu AA21004, an investigational drug for the treatment of adults with major depressive disorder (MDD) using dosages from 10 to 20mg.


Vitamin K2: New hope for Parkinson's patients?

Mon, 05/14/2012 - 00:00
Neuroscientist Patrik Verstreken, associated with VIB and KU Leuven, succeeded in undoing the effect of one of the genetic defects that leads to Parkinson's using vitamin K2. His discovery gives hope to Parkinson's patients.


FDA issues alert on potential dangers of unproven treatment for multiple sclerosis

Fri, 05/11/2012 - 13:00
The U.S. Food and Drug Administration is alerting health care professionals and patients about injuries and death associated with the use of an experimental procedure sometimes called "liberation therapy" or the "liberation procedure" to treat chronic cerebrospinal venous insufficiency (CCSVI).


GSK commences tender offer to acquire Human Genome Sciences for US $13.00 per share in cash

Fri, 05/11/2012 - 00:00
GlaxoSmithKline plc (LSE: GSK) today announced that it has commenced its previously announced tender offer to acquire all of the outstanding shares of Human Genome Sciences (NASDAQ: HGSI) for US$13.00 per share in cash.


Cancer Support Community launches national program to assist patients with cancer

Thu, 05/10/2012 - 00:00
The Cancer Support Community (CSC) and the Amgen Foundation, today announced the launch of Open to Options", a program designed to bridge the communications gap between physicians and patients and inspire patient confidence in making treatment decisions.


H1N1 discovery paves way for universal flu vaccine

Wed, 05/09/2012 - 00:00
University of British Columbia researchers have found a potential way to develop universal flu vaccines and eliminate the need for seasonal flu vaccinations. Each year, seasonal influenza causes serious illnesses in three to five million people and 200,000 to 500,000 deaths.


Some HDL, or 'good' cholesterol, may not protect against heart disease

Tue, 05/08/2012 - 00:00
A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called "good" cholesterol, may not protect against coronary heart disease (CHD) and in fact may be harmful.


Roche reports positive study of RoACTEMRA given by subcutaneous injection

Mon, 05/07/2012 - 00:00
Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that the SUMMACTA study met its primary endpoint, showing comparable efficacy of the subcutaneous (SC) formulation of RoACTEMRA (tocilizumab, known as ACTEMRA outside Europe) 162mg weekly compared to 8 mg/kg RoACTEMRA intravenous (IV) formulation every 4 weeks.


Abbott to Acquire Action Pharma's Investigational Compound, AP214

Fri, 05/04/2012 - 00:00
Abbott (NYSE: ABT) and Action Pharma A/S, a privately owned company, announced that they have entered into an agreement in which Abbott will acquire AP214 from Action Pharma. AP214 is in development to prevent acute kidney injury (AKI) associated with major cardiac surgery in patients at increased risk and has further potential in adjacent indications.


Sandoz to acquire Fougera Pharmaceuticals, becoming the number one generic dermatology medicines company

Fri, 05/04/2012 - 00:00
Novartis has signed a definitive agreement to acquire specialty dermatology generics company Fougera Pharmaceuticals. Under the terms of the agreement, Novartis will acquire the business, which is based in Melville, New York, for USD 1.525 billion in an all-cash transaction.


GlaxoSmithKline and Yale University establish drug discovery collaboration

Thu, 05/03/2012 - 00:00
GlaxoSmithKline plc (GSK) and Yale University have established a drug discovery research collaboration to design a potential new class of medicines that degrade disease-causing proteins. The collaboration combines GSK's expertise in medicinal chemistry with Yale's pioneering work on proteolysis targeting chimeric molecules or PROTACs.


Potential to revive abandoned cancer drug by nanoparticle drug delivery

Thu, 05/03/2012 - 00:00
Current nanomedicine research has focused on the delivery of established and novel therapeutics. But a UNC team is taking a different approach. They developed nanoparticle carriers to successfully deliver therapeutic doses of a cancer drug that had previously failed clinical development due to pharmacologic challenges.