The first clinical trial to compare two commonly used drugs head-to-head for venous thrombosis treatment has found a clear winner: while both drugs work well to prevent recurrent blood clots, apixaban is safer than rivaroxaban, with fewer bleeding complications.

Venous thrombosis occurs when a blood clot lodges in the veins of the legs or lungs.

A new discovery from researchers at The University of Texas at Austin and The University of Texas MD Anderson Cancer Center helps explain why some chemotherapy drugs not only eliminate cancer cells directly, they - at least in some patients - actually trigger the innate immune system to attack cancer cells.

The researchers made this discovery while testing a potential chemotherapy agent referred to as Compound 1 - which causes a build-up of toxic molecules called reactive oxygen species - on preclinical models.

A new study finds that combining the current medications for Alzheimer’s disease with small molecules derived from micronutrients found in grapes, berries, peanuts and turmeric is a safer and more effective way to treat the disease.

Individuals with Alzheimer’s have a buildup of toxic amyloid proteins in the brain. Researchers from the School of Pharmacy at the University of Waterloo combined amyloid-destroying small molecules with anti-amyloid antibodies that are already used in Alzheimer’s treatment.

Abbott (NYSE: ABT) announced today the launch of the second year of the 'Abbott Dream Team,' encouraging young soccer players aged 18-19 across the United States to sign up for the chance to take part in a once-in-a-lifetime development experience in Madrid. Selected participants will train with Real Madrid's world‑renowned coaches at the club's facilities and enjoy unique opportunities, including attending a Real Madrid match at the Bernabéu Stadium and meeting club legends.

A new experimental treatment for children with a hard-to-treat form of epilepsy is safe and can reduce seizures dramatically, helping them lead much healthier and happier lives, the findings of a UCL (University College London) and Great Ormond Street Hospital-led international clinical trial show.

In a new paper published in The New England Journal of Medicine, the researchers found that children with Dravet syndrome had up to 91 per cent fewer seizures while being regularly administered a new medication called zorevunersen.

Pfizer Inc. (NYSE: PFE) announced positive topline results from a Phase 2 study investigating tilrekimig (PF-07275315) in adults with moderate to severe atopic dermatitis. The study met its primary efficacy endpoint, demonstrating a statistically significant increase in the percentage of participants achieving EASI-75* (≥ 75% reduction in the Eczema Area and Severity Index) at Week 16, compared to placebo.

Medication nonadherence among people with chronic obstructive pulmonary disease (COPD) is a result of affordability and lack of knowledge about medications, among other factors, and leads to increased exacerbations and faster lung function decline, according to two new studies. The studies are published in the January 2026 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open access journal.

Researchers at the University of Bath have developed a new technology that uses bacteria to build, chemically stabilise, and test millions of potential drug molecules inside living cells, making it much quicker and easier to discover new treatments for difficult-to-treat cancers.

Researchers at Ohio University have discovered what may be a new way to fight lung cancer that is resistant to other treatments. The study published in the International Journal of Molecular Science and led by Goll-Ohio Eminent Scholar and distinguished professor John J. Kopchick, Ph.D., and his graduate student Arshad Ahmad at the Heritage College of Osteopathic Medicine, found that blocking the growth hormone receptor may help make lung cancer treatments more effective.

Cells have to break down sugar to produce energy. In most organisms, this process of glycolysis takes place in the cytosol. This is not the case with trypanosomes. These possess specialized organelles called glycosomes where glycolysis takes place. “Because the parasites rely fundamentally on these organelles for energy production, any disruption of glycosome biogenesis is lethal to them,” says Erdmann.

Daily aspirin use does not offer a quick or reliable way to prevent bowel cancer in the general population and carries immediate risks of serious bleeding, a new Cochrane review finds.

Bowel cancer, also known as colorectal cancer, is one of the most common types of cancer worldwide. Prevention typically involves following a healthy lifestyle and periodically undergoing routine screening tests.

Scientists have developed an adaptable materials platform that can safely and efficiently deliver a wide range of genetic medicines, a breakthrough that could accelerate the development of next‑generation vaccines, cancer treatments, and gene‑silencing drugs.

Experts from the University of Nottingham’s School of Pharmacy have created a new drug delivery platform that uses modular building blocks that self‑assemble with Ribonucleic acid- RNA to form nanoscale delivery particles.

Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat or vaccinate against illnesses. Many existing options rely on molecules with a strong positive charge, which can cause harmful inflammation. The team overcame this by using a neutral molecule and a new method to bind DNA to it, making it possible to deliver DNA into cells.

Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful compounds. In a new study, MIT chemical engineers have harnessed artificial intelligence to optimize the development of new protein manufacturing processes, which could reduce the overall costs of developing and manufacturing these drugs.

Pfizer Inc. (NYSE: PFE) today announced that the U.S. Food and Drug Administration (FDA) has granted full approval to BRAFTOVI® (encorafenib) in combination with cetuximab (marketed as ERBITUX®) and fluorouracil-based chemotherapy for the treatment of adult patients with metastatic colorectal cancer (mCRC) with a BRAF V600E mutation based on results from the global Phase 3 BREAKWATER trial (NCT04607421).

New antibody-drug conjugates (ADCs) developed at Institute of Science Tokyo combine a CD4 mimic with neutralizing antibodies for enhanced suppression of human immunodeficiency virus (HIV) infection. By targeting the gp120 on the viral envelope via a two-step mechanism, the ADCs effectively block viral entry - offering seven times better efficacy than existing approaches.

Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities. The Kobe University achievement is the result of a rational design strategy that yields a platform for the industrial production of drug candidates.

Plants produce many substances with promising pharmacological activities. For example, Rhododendron species produce a class of compounds, called orsellinic acid-derived meroterpenoids, with remarkable anticancer, anti-HIV, antidiabetic and anti-inflammatory activities.

A new study published by Mayo Clinic researchers suggests that ovarian cancer cells quickly activate a survival response after PARP inhibitor treatment, and blocking this early response may make this class of drugs work better.

PARP inhibitors are a common treatment for ovarian cancer and can be especially effective in cancers with impaired DNA repair.

Indiana University School of Medicine scientists have identified a promising drug target for Alzheimer's disease. The team found that removing an enzyme from neurons in the brain substantially reduces amyloid plaques - a hallmark characteristic of the disease - and may provide further resilience against disease progression.

Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, often driven by abnormal lipid metabolism and excessive blood vessel growth. In a new study, researchers from Fudan University and Wenzhou Medical University have uncovered how disulfiram - a long-used anti-alcoholism medication - exerts potent anti-tumor effects in liver cancer.