Ageing is defined as the deterioration of function overtime, and it is one of the main risk factors for numerous chronic diseases. Although ageing is a complex phenomenon affecting the whole organism, it is proved that the solely manifestation of ageing in the haematopoietic system affects the whole organism. Last September, Dr. M. Carolina Florian and her team revealed the significancy of using blood stem cells to pharmacologically target ageing of the whole body, thereby suggesting rejuvenating strategies that could extend healthspan and lifespan.
Rutgers neuroscientist Peng Jiang was visiting his hometown of Qianshan, a city in China’s Anhui province, when a neighbor came to his parents’ house with a story that would stay with him.
The man’s mother had been diagnosed with Alzheimer’s disease in her early 60s. After nearly a decade of decline, she no longer recognized her own son. One morning, she looked at him and asked gently, "How is your mother doing? Is she well?"
Researchers at the Paul Scherrer Institute PSI have clarified how spermine - a small molecule that regulates many processes in the body's cells - can guard against diseases such as Alzheimer's and Parkinson's: it renders certain proteins harmless by acting a bit like cheese on noodles, making them clump together. This discovery could help combat such diseases.